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Wellness Oncology & Hematology

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7320 Woodlake Ave, Ste 330
West Hills, CA 91307
Tarzana Office
5620 Wilbur Ave, Ste 219
Tarzana, CA 91356



Myelodysplastic Syndrome/ Myelodysplasia (MDS)

Myelodysplastic Syndromes are a specialized group of blood disorders that are caused by genetic abnormalities that lead to a clonal dysfunction of blood cells in the bone marrow. MDS is a very heterogenous condition with some people presenting with mild anemia while others present with a more aggressive drop in blood counts that can progress to overt leukemia. MDS typically affects people over the age of 70. A bone marrow biopsy is necessary to confirm the diagnosis. There are a number of treatments available to reduce and prevent complications from these diseases, including bone marrow transplants which can prove to be curative. In most people, however, bone marrow transplants may not be available and other supportive treatments are recommended.

There are many medications which are very helpful in treating patients with MDS, by stimulating the production of more blood cells. Transfusions of blood, including red cells and platelets may sometimes be necessary to replace low blood counts. There are also new treatments available which treat and improve the underlying condition so that a patient's own bone marrow can function better in producing its own blood cells. Treatments are highly personalized based on each patient's condition and needs. Given the wide range of options, Dr. Shaye, Dr. Lashkari, and Dr. Ho will review the details of each patient and their diagnosis to develop a personalized approach to patients with MDS.

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