An Oncologist in Tarzana, CA Treating Cancer and Blood Disorders Close to Home

Patient and caregiver reviewing a personalized oncology and hematology care plan binder in a comforting wellness lounge for an oncologist in Tarzana, CA.

Last Updated: September 15, 2026

Tarzana stretches along Ventura Boulevard and into the foothills near Caballero Canyon Trail, with Providence Cedars-Sinai Tarzana Medical Center serving as a major healthcare landmark in the community. Wellness Oncology & Hematology provides medical oncology and hematology care at 5620 Wilbur Avenue, Suite 219, just off Ventura Boulevard. The Tarzana team includes Omid Shaye, MD, Ashkan Lashkari, MD, and Christopher Ho, MD, who practice medical oncology and hematology. Conditions treated include lung, colon, breast, and prostate cancers, multiple myeloma, anemia, coagulation disorders, and other blood conditions. On-site services include infusion therapy, chemotherapy treatments, blood testing, and specialty pharmacy support.

Start Your Tarzana Appointment Call (818) 705-3900

A Tarzana Practice Where Oncology and Hematology Work Together

Medical oncology and hematology often intersect during cancer care. Multiple myeloma, leukemia, and lymphoma are hematologic cancers, while treatment for solid tumors can also affect red blood cells, white blood cells, platelets, and clotting. Dr. Shaye, Dr. Lashkari, and Dr. Ho practice both medical oncology and hematology, allowing related cancer and blood concerns to be evaluated through the same medical team, with additional specialists involved when needed.

People may seek oncology or hematology care after a new cancer diagnosis, an abnormal blood result, a referral for a suspected blood disorder, while receiving active treatment, or for a second opinion. Evaluation depends on the reason for referral and may involve reviewing laboratory results, pathology, imaging, previous treatment records, symptoms, and overall health before discussing appropriate next steps.

Oncology and Hematology Care Near Providence Cedars-Sinai Tarzana Medical Center in Tarzana

The Tarzana office is located at 5620 Wilbur Avenue, Suite 219, just off Ventura Boulevard and near Providence Cedars-Sinai Tarzana Medical Center. Providence identifies its medical center at 18321 Clark Street as a full-service Tarzana medical campus offering cancer and other specialty services. Wellness Oncology & Hematology remains a separate medical practice, and hospital-based care or services from other specialists may be coordinated separately when required by a patient’s treatment plan.

Cancer and blood disorder care can involve repeated appointments for consultations, infusions, chemotherapy, blood testing, or follow-up. The Wilbur Avenue office is located just off Ventura Boulevard and near Village Walk Shopping Center. Travel time and traffic vary by starting point and appointment time. Patients who need current parking, building-access, or arrival information can contact the Tarzana office before their visit.

Having infusion services, chemotherapy treatments, blood testing, and specialty pharmacy support available at the Tarzana office may allow selected parts of a treatment plan to be coordinated in one location. Surgery, radiation therapy, advanced imaging, stem cell transplantation, hospital care, or other specialist services may take place elsewhere depending on the diagnosis and individual treatment plan.

Oncology, Hematology, Infusion, and Support Services Available in Tarzana

When comparing oncology and hematology care, patients may consider physician training, board certification, available treatments, on-site services, clinical-trial access, language support, and location. The points below summarize key features of the Tarzana office.

Medical oncology and hematology physicians

Dr. Shaye, Dr. Lashkari, and Dr. Ho practice medical oncology and hematology. Dr. Shaye is certified in Internal Medicine and Medical Oncology, while Dr. Lashkari and Dr. Ho are certified in Internal Medicine, Medical Oncology, and Hematology

Cancer and blood disorder care

the team treats solid tumors alongside hematologic cancers such as multiple myeloma, leukemia, lymphoma, and myelodysplastic syndromes, as well as non-cancerous blood conditions including anemia and coagulation disorders. On-site blood testing may support evaluation and monitoring depending on the condition

On-site infusion and pharmacy support

infusion services, chemotherapy treatments, blood testing, and specialty pharmacy services are available at the office, allowing selected parts of a treatment plan to be coordinated in one location

Individualized treatment plans

each plan is shaped around the person’s specific diagnosis, stage, overall health, and preferences rather than a fixed formula

Support for comfort and quality of life

care includes attention to side-effect management, comfort, and overall wellness throughout oncology and hematology treatment

Access to multidisciplinary cancer treatment

depending on the diagnosis, stage, biomarkers, overall health, and individual patient, treatment may include chemotherapy, immunotherapy, targeted therapy, hormone therapy, or a clinical-trial option. Surgery and radiation therapy are coordinated with the appropriate specialists when indicated

Within Tarzana's medical corridor

the Wilbur Avenue office is near Providence Cedars-Sinai Tarzana Medical Center while remaining a separate oncology and hematology office

A multilingual team

the physicians speak English, Spanish, Farsi, and Chinese, which helps more South Valley families feel understood

Four Priorities That Shape Cancer and Blood Disorder Care in Tarzana

Care here is built around goals that carry through the whole journey. These are four of the things the team works toward, keeping in mind that every case is different and individual results vary.

Understanding Your Diagnosis and Options From the Start

The days after a diagnosis can be confusing, and clarity matters. The physicians review available pathology, imaging, laboratory results, and medical records to understand the diagnosis and stage, recommending additional testing when needed. From there, they explain the treatment options that fit the specific cancer or blood condition, including potential benefits and risks, so the plan can reflect both the medical findings and what matters most to the patient.

Managing Side Effects and Supporting Comfort During Treatment

How a patient feels day to day remains part of the treatment conversation. Depending on the therapy, side effects can include nausea, fatigue, appetite changes, or low blood counts, and supportive care may be used to prevent or manage selected treatment effects. Activity recommendations also vary. Patients hoping to keep up with ordinary routines, whether that means time with family or a gentle walk near Caballero Canyon Trail, should follow their oncology team’s guidance about exercise, fatigue, infection precautions, and other treatment-specific considerations.

Care That Fits Into Life in the South Valley

Frequent infusions, bloodwork, and follow-ups can mean repeated trips to the office. Having selected services on Wilbur Avenue, just off Ventura Boulevard, keeps those visits in Tarzana, while the number and length of appointments and whether additional care is needed elsewhere depend on the diagnosis and treatment plan. For patients and caregivers, knowing where each part of care will take place can make the schedule easier to plan.

One Team for Both Cancer and Blood Conditions

When cancer treatment affects the blood, or when a blood disorder needs ongoing attention, having oncologists who are also hematologists keeps the care connected. The same physicians can follow multiple myeloma, a treatment-related drop in counts, or a separate blood condition. That continuity helps a complex plan stay coordinated over time.

Inside the Cancer and Hematology Services Offered in Tarzana

Care is grouped into a few connected areas so patients can see how an evaluation turns into a plan. Medical oncology and hematology visits, chemotherapy, infusions, blood testing, and specialty pharmacy support are available through the Tarzana office. Surgery, radiation therapy, advanced imaging, stem cell transplantation, or hospital care may be coordinated with other specialists or facilities when those services are part of the plan.

Lung and Prostate Cancer Treatment

For lung cancer, the plan is guided by the cancer type, stage, biomarker or molecular findings, overall health, and treatment goals. Depending on those factors, care may involve surgery, radiation, chemotherapy, targeted therapy, immunotherapy, or a combination. Prostate cancer care is matched to disease risk and stage and may involve active surveillance, surgery, radiation, androgen-deprivation therapy, chemotherapy, or other systemic treatment. When surgery or radiation is part of the plan, those portions of care are coordinated with the appropriate specialists.

Breast and Colon Cancer Treatment

Breast cancer treatment depends on stage, tumor biology, hormone-receptor and HER2 status, overall health, and other individual factors and may combine surgery, radiation, chemotherapy, hormone therapy, targeted therapy, or immunotherapy. Colon cancer treatment is also stage-specific. Surgery is central to treatment for many localized colon cancers, while chemotherapy and, in selected situations, targeted therapy, immunotherapy, or radiation may also be used. The combination depends on the individual diagnosis rather than a fixed sequence.

Multiple Myeloma and Other Blood Cancers

Multiple myeloma is a blood cancer that may require treatment over time, with the plan shaped by disease features, symptoms, previous therapy, overall health, and whether stem cell transplantation is appropriate. Treatment can include targeted therapies, immunotherapies, corticosteroids, chemotherapy, and supportive care. For selected patients, hematopoietic stem cell transplantation, often using the patient’s own stem cells, may be considered, while radiation can be used for certain bone lesions or symptoms. The team also treats blood cancers such as leukemia and lymphoma.

Hematology Care for Anemia and Blood Disorders

As hematologists, the physicians evaluate non-cancerous blood conditions such as anemia and coagulation disorders, along with bone marrow cancers including myelodysplastic syndromes, or MDS. Blood testing can help narrow down the cause of anemia or abnormal counts, with additional testing used when needed. Treatment depends on the condition and may range from supplements or medications to infusions, transfusions, or disease-specific therapy.

Cancers and Blood Conditions the Tarzana Team Treats

Additional Treatment and Support Available in Tarzana
  • On-site chemotherapy and infusion services
  • On-site blood testing and a specialty pharmacy
  • Clinical trial options when appropriate

The Board-Certified Doctors Who Will Guide Your Tarzana Care

Three physicians who practice medical oncology and hematology share care at the Tarzana office, each bringing a personalized, patient-centered approach. Dr. Shaye is certified in Internal Medicine and Medical Oncology, while Dr. Lashkari and Dr. Ho are certified in Internal Medicine, Medical Oncology, and Hematology.

Omid S. Shaye, MD: Practice Founder, Oncologist, and Hematologist

A native of the San Fernando Valley, Dr. Omid Shaye founded Wellness Oncology & Hematology after training close to home. He completed both his undergraduate degree and his medical degree at the University of Southern California, then his residency and a hematology and oncology fellowship at the USC Norris Cancer Center, where he served as chief fellow of medical oncology. He often describes himself as the quarterback of a patient’s care, coordinating individualized treatment that can include targeted therapies, clinical trials, immunotherapy, chemotherapy, radiation, and surgery. Dr. Shaye is certified by the American Board of Internal Medicine and the American Board of Medical Oncology, belongs to the Medical Oncology Association of Southern California, the Community Oncology Alliance, and the American Society of Clinical Oncology, and speaks English, Spanish, and Farsi.

Ashkan Lashkari, MD: Oncologist and Hematologist

Dr. Ashkan Lashkari offers personalized oncology and hematology care and stayed close to home for his training, earning bachelor’s degrees in art history and molecular biology and then his medical degree at the University of California, Los Angeles. He completed an internal medicine residency at UCLA and a fellowship in hematology and medical oncology at the City of Hope Comprehensive Cancer Center, where he concentrated on designing clinical trials and studying familial cancer syndromes. He is certified by the American Board of Internal Medicine, the American Board of Medical Oncology, and the American Board of Hematology, serves as an assistant clinical faculty member at Olive View-UCLA Medical Center, holds membership in the American Society of Hematology and the American Society of Clinical Oncology, and speaks English and Farsi.

Christopher Ho, MD: Oncologist and Hematologist

Dr. Christopher Ho completed his undergraduate studies at Johns Hopkins University and earned his medical degree at Temple University, where a clerkship at the Fox Chase Cancer Center drew him toward medical oncology research. He finished an internal medicine residency at the University of California, Davis, then subspecialty training in medical oncology and hematology at the University of Southern California’s Keck School of Medicine, serving as chief fellow of medical oncology. Dr. Ho is certified by the American Board of Internal Medicine, the American Board of Medical Oncology, and the American Board of Hematology, holds membership in the American Society of Hematology and the American Society of Clinical Oncology, and centers his care on a comprehensive, personalized approach. He speaks English, Spanish, and Chinese.

Quick Answers for Tarzana Patients Considering a Visit

Where exactly is the Tarzana office located?

The office is at 5620 Wilbur Avenue, Suite 219, just off Ventura Boulevard and a short distance from the Providence Cedars-Sinai Tarzana Medical Center. It sits within Tarzana’s medical corridor, near the shops and dining of the Village Walk Shopping Center.

Can infusions, chemotherapy, and blood work be done at the Tarzana office?

Yes. The Tarzana location offers on-site infusion services, chemotherapy treatments, blood testing, and specialty pharmacy support. Other parts of a treatment plan, such as surgery, radiation therapy, advanced imaging, stem cell transplantation, hospital care, or services from other specialists, may take place at another facility when needed.

What parking is available near the Wilbur Avenue office?

Wilbur Medical Plaza lists visitor parking at the property, along with metered and non-metered street parking nearby. Availability can vary, so patients who need current parking or arrival information can contact the Tarzana office before their visit.

Tarzana and South Valley Areas Near the Wilbur Avenue Office

The Wilbur Avenue office serves Tarzana and surrounding South San Fernando Valley communities. Relevant local areas and landmarks include:

  • Tarzana, CA (91356)
  • South Tarzana and the Caballero Canyon Trail area
  • The Ventura Boulevard and Village Walk Shopping Center corridor
  • The Providence Cedars-Sinai Tarzana medical corridor
  • Melody Acres
  • Braemar
  • Encino
  • Sherman Oaks
  • The greater South San Fernando Valley

A Practice That Belongs to the Tarzana Neighborhood

Life in Tarzana tends to move between the everyday bustle of Ventura Boulevard, errands at Village Walk Shopping Center, and weekend time around Caballero Canyon Trail, with Providence Cedars-Sinai Tarzana Medical Center as a familiar healthcare landmark. A cancer or blood disorder diagnosis can add consultations, infusions, blood tests, and follow-up visits to that routine. Having the Wilbur Avenue office in Tarzana keeps selected oncology and hematology services within the neighborhood, while the number, length, and location of visits depend on the diagnosis and treatment plan. 

Hearing From Patients Treated at Wellness Oncology & Hematology

These reviews describe individual patient experiences. Diagnosis, treatment recommendations, side effects, response to therapy, prognosis, and outcomes vary from person to person.

“Dr. Ho displays that all-too-rare balance of being both professional and personable. He is extremely knowledgeable and effectively explains things, often with analogies. Plus, I found him to be warm and engaging. I did not feel rushed, and the office staff was friendly”

- Ira Heffler

“Everybody at the office was amazing. From the scheduling to intake to the nurse, everyone was courteous, professional and kind. They even scheduled my exams at other labs for me. Dr. Ho is extremely thoughtful, thorough and compassionate. I have never felt in better hands.” 

- Sam Jones

“Dr. Shaye is an incredible oncologist. He is kind, thorough and I felt very safe being in his hands. I still speak of him to this day (12 years later) with fondness. Wonderful doctor!”

- Victoria Thomas

Book a Consultation With the Tarzana Cancer Care Team

Call (818) 705-3900 or schedule online to start a consultation with the Tarzana team. The office can explain what to expect at a first oncology or hematology visit, tell you which medical records, pathology reports, imaging, or laboratory results should be sent or brought, and confirm whether blood testing, an infusion, or another service is scheduled at the Wilbur Avenue office.

  • Address: 5620 Wilbur Ave Ste 219, Tarzana, CA 91356
  • Website: https://www.wellnessoncology.com/
  • Hours: Monday to Friday, 8:30 AM to 5:30 PM. Closed Saturday and Sunday.

Wellness Oncology & Hematology 5620 Wilbur Ave Ste 219, Tarzana, CA 91356

Start Your Tarzana Appointment Call (818) 705-3900

Answers From an Oncologist in Tarzana, CA on Cancer and Blood Care

Persistent anemia or low hemoglobin is typically evaluated by a hematologist, a physician who specializes in blood conditions. At Wellness Oncology & Hematology, the same physicians who treat cancer are also hematologists, so they can investigate the cause and manage treatment. On-site blood testing helps identify what is behind the low counts.

Persistently high, low, or unexplained blood counts may warrant a hematology evaluation, especially when the abnormality continues on repeat testing or appears with symptoms such as fatigue, easy bruising, unusual bleeding, or frequent infections. Whether a hematologist is needed depends on the type and degree of the abnormality, symptoms, medical history, medications, and other findings.

Finding the cause of anemia usually starts with blood tests that look at red blood cell size, iron levels, vitamin levels, and other markers, sometimes followed by additional testing. Anemia can stem from nutritional deficiencies, chronic conditions, blood loss, or bone marrow issues. Identifying the underlying reason is what guides the right treatment.

Possible signs of leukemia in adults include persistent fatigue, frequent infections, easy bruising or bleeding, unexplained weight loss, night sweats, and swollen lymph nodes. These symptoms can have many causes, so they are not proof of leukemia. Bloodwork and, when needed, a bone marrow evaluation help clarify what is going on.

All three are blood cancers, but they affect different cells. Leukemia generally arises in the blood and bone marrow, lymphoma develops in the lymphatic system, and multiple myeloma involves plasma cells in the bone marrow. Each is diagnosed and treated differently, which is why an accurate hematologic workup matters.

Evaluating multiple myeloma commonly involves blood and urine tests, imaging, and bone marrow testing. These studies help confirm the diagnosis and assess the amount and features of disease. Multiple myeloma staging also uses specific blood-test findings, including beta-2-microglobulin and albumin levels. The results are considered together when the stage and treatment plan are determined.

Colon cancer treatment is guided closely by stage, tumor features, overall health, and whether the cancer has spread. Surgery is a main treatment for many localized colon cancers. Chemotherapy is commonly used in stage III disease and selected higher-risk situations, while targeted therapy, immunotherapy, radiation, or other approaches may be used in certain cases. The treatment combination depends on the individual diagnosis.

The choice depends on the cancer type, its stage, and specific features found through testing of the tumor. Chemotherapy works broadly against rapidly dividing cells, targeted therapy acts on particular molecular changes, and immunotherapy helps the immune system attack the cancer. Often these are combined, and the plan is personalized to each patient.

Biomarker testing looks for genes, proteins, or other features of a cancer that may help guide treatment. In some cancers, the results can help identify targeted therapies, immunotherapies, or clinical trials that may be appropriate. Biomarker testing is not needed for every cancer, and finding a particular biomarker does not guarantee that a treatment will work. Your oncologist can explain whether this testing is relevant to your diagnosis.

A second opinion can be considered whenever you want another specialist to review the diagnosis or treatment plan, particularly with a rare or complex cancer or when several treatment options are available. Another oncologist may confirm the original recommendation or discuss a different approach. Ask the offices involved which pathology reports, imaging, laboratory results, and other records should be provided for the review.

The Tarzana office treats a wide range of cancers, including lung, colon, breast, prostate, and multiple myeloma, along with leukemia, lymphoma, and others. On the hematology side, the team cares for anemia, coagulation disorders, and myelodysplastic syndromes (MDS)/myelodysplasia, among other blood conditions. On-site infusions, chemotherapy, testing, and a specialty pharmacy support that care.

Yes. Dr. Shaye, Dr. Lashkari, and Dr. Ho all practice medical oncology and hematology at the Tarzana office. Dr. Shaye is certified in Internal Medicine and Medical Oncology, while Dr. Lashkari and Dr. Ho are certified in Internal Medicine, Medical Oncology, and Hematology. Depending on the diagnosis, the same physician may be able to address related oncology and hematology concerns, with other specialists involved when needed.

Bring a photo ID and insurance card, a list of your current medications, and any relevant records, such as recent bloodwork, imaging, pathology reports, or a referral if you have one. It also helps to write down your questions and, if you like, bring a family member. The office can help request records you are missing.

A first visit may include a detailed review of your medical history, symptoms, medications, and available test results, along with a physical exam or blood testing when appropriate. Your physician can discuss what the available findings mean, answer questions, and explain possible next steps. Additional testing, pathology review, imaging, or consultation with another specialist may be recommended before a treatment plan is finalized.

An oncology or hematology consultation may be appropriate after a new cancer diagnosis, a suspicious finding, persistent or unexplained blood-count abnormalities, or a referral from another clinician. Wellness Oncology & Hematology is welcoming new patients. Appointment timing depends on availability, the reason for referral, and which records are needed for review, so call the Tarzana office to ask about the next available consultation.

Bringing Advanced Cancer and Hematology Care Home to Tarzana

If you want a team that will hear your concerns fully, explain your diagnosis and appropriate treatment options in language that makes sense, and consider comfort and side-effect management alongside cancer or blood disorder treatment, the physicians at Wellness Oncology & Hematology are here to help. Whether you are facing a new diagnosis, an unexplained blood result, or want a second opinion, reach out when you are ready to talk.

Speak With the Tarzana Care Team Today

Wellness Oncology & Hematology 5620 Wilbur Ave Ste 219, Tarzana, CA 91356

https://www.wellnessoncology.com/

Hours:

  • Monday to Friday: 8:30 AM to 5:30 PM
  • Saturday and Sunday: Closed